The new studies (linked directly below) found Creatine to:

Support muscle and function even without exercise. In studies of older adults and immobilized limbs, creatine users maintained more lean tissue and strength than non-users. One trial found older adults taking creatine for 32 weeks preserved leg-press and chest-press strength despite periods of reduced activity.

Enhance bone strength and density. Research in aging populations shows creatine combined with resistance training can increase bone area and estimated strength, helping counter osteoporosis risk. These effects have been reported in older adults over 6–12 months of supplementation and training.

Improve cognition and memory. Studies in healthy older adults and early-stage Alzheimer’s patients show modest improvements in memory and mental fatigue resistance after creatine loading. Other trials report better cognitive performance during sleep deprivation in young adults, suggesting creatine helps stabilize brain energy when under stress.

Promote healthy aging. A 2025 review concluded creatine supplementation increases lean mass, regional muscle size, and functional ability in older adults - particularly when paired with exercise. It also improves glucose kinetics in some studies, suggesting a role in preventing age-related metabolic decline.

Support women’s health across life stages. New research highlights benefits for exercise performance and fatigue resistance across the menstrual cycle. Early human studies are now investigating pregnancy applications, while postmenopausal trials indicate gains in muscle and bone similar to those seen in men.

Aid recovery and tissue repair. In trials of patients recovering from injury or surgery, creatine supplementation reduced muscle loss and improved functional recovery. Animal and pediatric studies also suggest creatine may shorten recovery time and lessen brain damage after traumatic brain injury.

Increase muscle strength, size, and performance - You probably already knew this, but the new studies found that adults supplementing with 3–5 grams of creatine daily while resistance training gained significantly more strength and lean mass than placebo groups - improvements often ranging from 5–15% greater increases in performance metrics after 8–12 weeks of training.

https://www.zerohedge.com/medi....cal/pivotal-research